Bioorganic and Medicinal Chemistry Letters p. 1833 - 1838 (1998)
Update date:2022-08-24
Topics:
Saladino, Raffaele
Danti, Maria Chiara
Mincione, Enrico
Crestini, Claudia
Palamara, Anna Teresa
Savini, Patrizia
Marini, Stefano
Botta, Maurizio
Several new 6-oxiranyl-, 6-methyloxiranyluracils, and pyrimidinone derivatives, synthesized by the lithiation-alkylation sequence of 1,3,6- trimethyluracil, 1,3-dimethyl-6-chloromethyluracil, and 2-alkoxy-6-methyl- 4(3H)-pyrimidinones, showed a potent and selective antiviral activity against the parainfluenza 1 (Sendai) virus replication.
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