Journal of Pharmaceutical Sciences p. 1199 - 1203 (1992)
Update date:2022-08-29
Topics:
Gala
Puar
Das
Kugelman
DiBenedetto
α-Hydroxyaryl ketones such as 2-hydroxypropiophenone and 1-(2,4- difluorophenyl)-2-hydroxy-1-propanone, the key intermediates in the preparation of antifungal agents, decompose into oxidized, rearranged, and condensed products. These products were isolated and characterized. The possible mechanisms for the formation of the products are discussed.
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