Synthesis and antituberculous activity of N-Mannich bases of 3-[4-(4-chlorophenyl)-6-(4-methylphenyl) pyrimidin-2-yl] iminoisatin derivatives

Article abstract of DOI:10.3797/scipharm.aut-02-05

Isatin, its 5-chloro and 5-bromo derivatives have been reacted with 4-(4-cholorophenyl)-6-(4-methylphenyl)-2-aminopyrimidine to form Schiff bases and the N-Mannich bases of these compounds were synthesized by reacting them with formaldehyde and several se