Preparation and synthetic applications of sterically hindered secondary amines

Article abstract of DOI:10.1080/00397919708004114

The preparation of sterically hindered secondary amino esters from the reaction of N-protected α-amino aldehydes and 3-, or 2-oxo esters with α- amino esters by reductive amination is described. The resulting amino esters were converted to the β-lactam or acylated to form N-acyl secondary amides.

Full text of DOI:10.1080/00397919708004114

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Preparation and Synthetic
Applications of Sterically
Hindered Secondary Amines
Hwa-Ok Kim a , Brian Carroll a & Min S. Lee a
a Molecumetics , 2023 120th Ave. N.E., Suite 400,
Bellevue, WA, 98005-2199
Published online: 21 Aug 2006.
To cite this article: Hwa-Ok Kim , Brian Carroll & Min S. Lee (1997) Preparation
and Synthetic Applications of Sterically Hindered Secondary Amines, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 27:14, 2505-2515, DOI: 10.1080/00397919708004114
To link to this article: http://dx.doi.org/10.1080/00397919708004114
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