A New Stereocontrolled Route to trans-2,5-Disubstituted Tetrahydrofurans

DOI: 10.1246/cl.1992.195

Source and publish data:

Chemistry Letters p. 195 - 198 (1992)

Update date:2022-08-15

Topics:

Authors:

Chikashita, Hidenori

Yasuda, Hiroyuki

Kimura, Yasunori

Itoh, Kazuyoshi

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Article abstract of DOI:10.1246/cl.1992.195

An effective new route for the stereocontrolled synthesis of trans-2,5-disubstituted tetrahydrofurans was described, which involved a new type of 1,4-asymmetric induction based on the addition of originally designed dithianyl anion to aldehydes and a stereocontrolled cyclodehydration of the resulting 1,4-diols.

Full text of DOI:10.1246/cl.1992.195

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