E- and Z-β-Formylvinyl Synthons from 1-Tributylstannyl-3,3-diethoxy-prop-1-ene via Cross Coupling with Acid Chlorides

Article abstract of DOI:10.1016/S0040-4039(00)73930-X

The easily prepared and stored E-1-tributylstannyl-3,3-diethoxy-prop-1-ene 1E reacts with acyl chlorides in DMF in the presence of PdCl2(MeCN)2 to give the expected 1,4-ketoacetals (E isomers).Similarly cross coupling of 1E with tosyl chloride performed i