Journal of Organic Chemistry p. 4542 - 4547 (1994)
Update date:2022-08-11
Topics:
Uesaka, Noriaki
Mori, Miwako
Okamura, Kimio
Date, Tadamasa
The catalytic cyclization of the diene 1 by Cp2ZrCl2 in the presence of BuMgBr gives the hexahydroindole derivative 2.The stereochemistry of the zirconacycle 10 is different from that of the zirconacycle 7, which is obtained from 1 under stoichiometric conditions.Carbon-carbon bond formation results from treatment of the intermediary magnesium complex 8 with various electrophiles, such that various heterocycles were synthesized.
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