Organic Process Research and Development p. 1274 - 1281 (2015)
Update date:2022-08-11
Topics:
Moccia, Maria
Cortigiani, Mauro
Monasterolo, Claudio
Torri, Federica
Del Fiandra, Claudia
Fuller, Geoffrey
Kelly, Brian
Adamo, Mauro F. A.
Herein is reported the development of a new process to manufacture (S)-pregabalin. The method comprises six steps, run under the catalysis of a recyclable polymer bound phase transfer catalyst, and afforded (S)-pregabalin in overall 54% yield, starting from building blocks acetylacetone, isovaleraldehyde, and nitromethane.
View MoreNanjing Chemical Material Corp.(NCMC)
website:http://www.njchemm.com
Contact:0086-25-83172879
Address:B12 Technology and Innovation Building, Nanjing Tech University, No.5 New Model Road
Liaoning Yufeng Chemical Co.,Ltd.
Contact:86-0419-3418888
Address:The metallurgical industrial zone,shoushan town, Liaoyang, Liaoning, China
PINGYUAN SIHUAN PHARMACEUTICAL CO., LTD
Contact:+86-531-55696072
Address:#2766,yinxiu Road, Economic Development Zone, Pingyuan Country, Shandong Province, China.
website:http://www.hanwayschem.com
Contact:+86-18502787239(whatsapp)
Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China
SHANGHAI ARCADIA BIOTECHNOLOGY LTD.
Contact:+86-21-61353236
Address:SUITE 901, BUILDING WENSLI, 1378 LU JIA BANG RD, SHANGAHI 200011, P.R.CHINA
Doi:10.1021/ja00457a040
(1977)Doi:10.1021/tx9003769
(2010)Doi:10.1039/c2nj40666g
(2012)Doi:10.1039/C8DT04195D
(2019)Doi:10.1007/BF01516522
(1881)Doi:10.1246/bcsj.57.2683
(1984)