Abid et al.
Antimicrobial Efficacy of Synthesized Quaternary Ammonium PAMAM Dendrimers and Dendritic Polymer Network
polymer network (poly(PAMAM G1.0-EGDMA) Q OI)
showed significant antimicrobial activity against Gram-
positive and Gram-negative bacteria. 5 mg/L water soluble
PAMAM G1.0 QHCl was found to be efficient to disin-
fect all types of tested bacteria within an incubation time
of just 2 minutes. Moreover, 10 mg/L of water insolu-
ble poly(PAMAM G1.0 EGDMA) QOI also disinfected
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ABBREVIATIONS
QAC Quaternary ammonium compounds
2
5. P. Singh, U. Gupta, A. Asthana, and N. K. Jain, Bioconjugate Chem.
G
Q
Generation
Quarternized
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Delivered by Publishing TechnologySctio. :1 1M5 ,c7 M1 6a( s2 t0 e1 0r ) U. niversity
PAMAM Polyamido amine
OI Octyl iodide
PAMAM-EGDMA Polyamido amine-ethylene glycol
IP: 177.10.125.205 On: We d2 ,7 .0 C9 . MZ . aC rh 2e n0 a1 n 6d S0 .9 L: .2 C3 o: o0 p2e r, Biomaterials 23, 3359 (2002).
Copyright: American S 2c 8i .e nM t i. fi cK .P Cu abl al bi sr eht tea ,r sA. Kumar, A. M. McDermott, and C. Ca,
Biomacromolecules 8, 1807 (2007).
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Acknowledgment: Financial support from Lockheed
Martin Corporation (NJ, U.S.A.) is gratefully acknowl-
edged. Authors are also thankful to CSIR, ICMR and
UGC, Government of India, for their senior research and
post-doctoral fellowships.
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Received: 23 April 2014. Accepted: 10 October 2014.
J. Nanosci. Nanotechnol. 16, 998–1007, 2016
1007