A two-step asymmetric synthesis of pure trans-(R,R)-diaryl-epoxides

Article abstract of DOI:10.1016/0957-4166(96)00213-3

Pure trans-(R,R)-diaryl-epoxides are obtained in two steps and under aprotic conditions using Eliel's oxathiane as the chiral auxiliary. The enantiomeric excesses, determined by chiral HPLC, are 97.9% to 99.9% and the oxathiane is recovered in 78% to 92% yield and may thus be re-used.