Enantioselective reduction of acetophenone with 1,3,2-oxazaborolidines derived from ephedrine, pseudoephedrine, and phenylglycine

Article abstract of DOI:10.1016/S0957-4166(00)86005-X

The performance of several 1,3,2-oxazaborolidines as chiral catalysts in the reduction of acetophenone has been compared, to gain insight into the more relevant structural factors as far as yield and enantioselectivity are concerned. B-Alkyl-4,5,5-triphen