Sn(II)Cl2-induced regiospecific opening of the 1,3-benzodioxole ring system: A route to the novel DNA-interactive ligand iso-DC-81

DOI: 10.1016/S0040-4039(00)91800-8

Source and publish data:

Tetrahedron Letters p. 1377 - 1378 (1993)

Update date:2022-08-31

Topics:

Authors:

Bose Bose

Thurston

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Article abstract of DOI:10.1016/S0040-4039(00)91800-8

A novel tin-catalysed regiospecific cleavage of a 1,3-benzodioxole ring system is reported that has been applied to the synthesis of a uniquely-substituted DNA-binding pyrrolo[2,1-c][1,4]benzodiazepine antitumour agent, iso-DC-81(4a).

Full text of DOI:10.1016/S0040-4039(00)91800-8

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