Tetrahedron Letters p. 2219 - 2222 (1998)
Update date:2022-08-11
Topics:
Kerrigan, Frank
Martin, Claire
Thomas, Gerard H.
Reaction of a series of bicyclic bromoarenes with N-tert- butoxycarbonylpiperazine (N-Boc-piperazine) under palladium-catalysed coupling conditions followed by routine removal of the Boc group with trifluoroacetic acid in dichloromethane gave the corresponding arylpiperazines in moderate to good yield.
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