Cerium(III) chloride mediated regioselective synthesis of cyclic α- chloro-α,β-enones and α-chloro-β-hydroxy ketones

Article abstract of DOI:10.1016/S0040-4039(99)01129-6

Reaction of cyclic α,β-epoxy ketones with Ce(III) chloride under hydrous or anhydrous conditions yields the corresponding cyclic α-chloro- α,β-enones or cyclic α-chloro-β-hydroxy ketones, respectively.