Use of 2-pyridyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D-glucopyranoside as a glycosyl donor and methyl iodide as an activator for the synthesis of 1,2-trans-linked saccharides

Article abstract of DOI:10.1016/0008-6215(93)80041-C

The authors report on the successful use of 2-pyridyl 2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-1-thio-β-D- glucopyranoside as a glycosyl donor and methyl iodide as an activator for the synthesis of 1,2-trans-linked saccharides. This synthesis is significant because the 2-amino-2-deoxyglycopyranosides are important constituents of glycoproteins, glycolipids and glycoside antibiotics. All known for their biological functions like antigen-antibody reactions and in cell communication.