Direct Total Syntheses of Frenolicin B and Kalafungin via Highly Regioselective Diels-Alder Reactions

DOI: 10.1021/jo00110a017

Source and publish data:

Journal of Organic Chemistry p. 1154 - 1159 (1995)

Update date:2022-08-17

Topics:

Authors:

Kraus, George A.

Li, Jun Li, Jun

Gordon, Mark S.

Jensen, Jan H.

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Article abstract of DOI:10.1021/jo00110a017

Frenolicin B, an anticoccidial agent, has been synthesizes in six steps from ketone 3.Racemic kalafungin, an antifungal agent, has been synthesized in five steps.The key step in both syntheses, a regioselective Diels-Alder reaction, proceeds with complete

Full text of DOI:10.1021/jo00110a017

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