Synthetic Communications p. 1819 - 1825 (1997)
Update date:2022-08-16
Topics:
Evans, Emily F.
Lewis, Norman J.
Kapfer, Isabelle
Macdonald, Gregor
Taylor, Richard J. K.
A mild and efficient procedure is described for the removal of the tert- butoxycarbonyl (BOC) group using boron trifluoride etherate and molecular sieves in dichloromethane at room temperature. The scope of this procedure is explored for the deprotection of a variety of amines including amino acid derivatives.
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