Synthesis of 1→6,1→4 and 1→3 linked 1-thio-α-L-fucopyranosyl 2-acetamido-2-deoxy-β-D-glucopyranosides and 1→2 linked β-D-galactopyranoside, and their linkage-specific inhibitory activities toward α-L-fucosidases

Article abstract of DOI:10.1016/S0040-4039(00)74055-X

Sulfur-linked disaccharides analogs of three α-L-fucopyranosyl 2-acetamido-2-deoxy-β-D-glucopyranosides and one α-L-fucopyranosyl β-D-galactopyranoside were synthesized by substitution reactions of sulfonates and ring-opening reactions of aziridiene as we