Tetrahedron Letters p. 3235 - 3238 (1993)
Update date:2022-08-10
Topics:
Paquette, Leo A.
Schulze, Matthias M.
Metalation of 4a and 4b with n-butyllithium under kinetically controlled conditions (C5H6, 20 °C or Et2O, TMEDA (2 equiv), 20 °C) leads to preferred deprotonation α to the heterocyclic ring.
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