Synthesis, binding properties, and 18F labeling of fluorocarazolol, a high-affinity β-adrenergic receptor antagonist

Article abstract of DOI:10.1021/jm00046a005

New β-adrenergic receptor antagonists, 2-(R)-(+)- and 2-(S)-(-)-1-(9H- carbazol-4-yl-oxy)-3-[[1-(fluoromethyl)ethyl]amino]-2-propanol ((S)- and (R)- fluorocarazolols), were labeled with fluorine-18 at the no-carrier-added level by reductive alkylation of