4'-Thio-RNA: Synthesis, base pairing properties and interaction with dimerization initiation site of HIV-1

Article abstract of DOI:10.1080/07328319908044740

In the present paper, we describe the synthesis of a modified 9-mer oligonucleotide, 4'-S-r(UGUGCACCU) containing for the first time 4'-thio- guanosine units. This modified 9-mer was found to inhibit in vitro genomic RNA dimerization as well as the wild type RNA.

Full text of DOI:10.1080/07328319908044740

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Nucleosides and Nucleotides
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4′-Thio-RNA: Synthesis, Base Pairing
Properties and Interaction with
Dimerization Initiation Site of HIV-1
b
b
a
David Dukhan , Florence De Valette , Roland Marquet , Bernard
a
a
b
Ehresmann , Chantal Ehresmann , François Morvan , Jean-Louis
b
b
Barascut & Jean-Louis Imbach
a
Institut de Biologie Moléculaire et Cellulaire , 15 rue René,
Descartes, 67084, Strasbourg
b
Laboratoire de Chimie Bio-organique , E. Bataillon, 34095,
Montpellier, France
Published online: 04 Oct 2006.
To cite this article: David Dukhan , Florence De Valette , Roland Marquet , Bernard Ehresmann ,
Chantal Ehresmann , François Morvan , Jean-Louis Barascut & Jean-Louis Imbach (1999) 4′-Thio-
RNA: Synthesis, Base Pairing Properties and Interaction with Dimerization Initiation Site of HIV-1,
Nucleosides and Nucleotides, 18:6-7, 1423-1424, DOI: 10.1080/07328319908044740
To link to this article: http://dx.doi.org/10.1080/07328319908044740
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