Tetrahedron Letters p. 1775 - 1778 (1992)
Update date:2022-08-10
Topics:
Rabanal, Francesc
Giralt, Ernest
Albericio, Fernando
N-<9-(hydroxymethyl)-2-fluorenyl> succinamic acid may be used as an anchoring linkage for the preparation of protected peptide segments in combination with Boc/Bzl protection scheme.The new handle proved to be stable to the usual conditions of solid-phase peptide synthesis and gave the protected peptide in high yields and purities by treatment with piperidine or morpholine.
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