Kinetic Studies on the Reaction of Cyanuric Chloride with Amines

Article abstract of DOI:10.1002/prac.19953370128

The individual steps in the reactions of cyanuric chloride with n-butyl amine in N-methyl pyrrolidone (NMP) and with morpholine in isopropanol (i-PrOH) were followed kinetically.The ratio of the exchange rates of the first, the second and the third chlorine atom was unexpectedly high in both cases.The reactions of n-butylamino dichlorotriazine with several amines were studied kinetically both in NMP and in i-PrOH.Linear free-energy relationships exist both between our values and reaction rates of p-nitro fluorobenzene with the corresponding amines (in DMSO) determined by Suhr.