Journal of Organic Chemistry p. 2378 - 2383 (1995)
Update date:2022-08-16
Topics:
Cliff, Matthew D.
Pyne, Stephen G.
A method for preparing trihydroxybutyl analogues of the biologically active compound 2-acetyl-4(5)-(1,2,3,4-tetrahydroxybutyl)imidazole (THI) is reported.This method employs a palladium(0)-catalyzed coupling of 1-(ethoxymethyl)-4-iodoimidazole (3a) to fun
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