Antitumour activity of S-p-bromobenzylglutathione cyclopentyl diester in vitro and in vivo. Inhibition of glyoxalase I and induction of apoptosis

DOI: 10.1016/0006-2952(96)00059-7

Source and publish data:

Biochemical Pharmacology p. 1365 - 1372 (1996)

Update date:2022-08-11

Topics:

Authors:

Thornalley, Paul J.

Edwards, Linda G.

Kang, Yubin

Wyatt, Catherine

Davies, Nathan

Ladan, Muhatri J.

Double, John

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Article abstract of DOI:10.1016/0006-2952(96)00059-7

The glyoxalase I inhibitor diester, S-p-bromobenzyl-glutathione cyclopentyl diester (BrBzGSHCp₂), inhibited the growth of human leukaemia 60 (HL60) cells in vitro. The median growth inhibitory concentration GC₅₀ value of BrBzGSHCp View More

Full text of DOI:10.1016/0006-2952(96)00059-7

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