Isolation of Five-Membered Cyclitol Glycolipids, Crasserides: Unique Glycerides from the Sponge Pseudoceratina crassa

Article abstract of DOI:10.1021/jo00053a034

Crasserides 1a-6a, six new glycolipid analogues in which the sugar moiety is replaced by an unprecedented five-membered cyclitol, were isolated as a mixture from the sponge Pseudoceratina crassa (Hyatt), and their structures were determined by spectroscopic and chemical analysis.Compounds 1a-6a showed a high antifeedant activity on the fish Carassius auratus, which suggests their potential role as natural feeding deterrents.