Total synthesis of tryprostatin A and B as well as their enantiomers

DOI: 10.1016/S0040-4039(98)01466-X

Source and publish data:

Tetrahedron Letters p. 7009 - 7012 (1998)

Update date:2022-08-17

Topics:

Authors:

Zhao, Shuo

Gan, Tong

Yu, Peng

Cook, James M.

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Article abstract of DOI:10.1016/S0040-4039(98)01466-X

The 3-methylindoles 3a, 3b were convened into tryprostatin A (1a), B (1b) and their enantiomers 2a, 2b via prenylation at the indole 2-position by generation of the required 2-lithioindole derivatives (from 7a, 7b), followed by alkylation.

Full text of DOI:10.1016/S0040-4039(98)01466-X

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