Efficient masking of p-benzoquinone in nitrone cycloaddition chemistry

Article abstract of DOI:10.1016/0040-4039(95)01787-I

1,3-Dipolar cycloadditions of five and six membered cyclic nitrones to p-benzoquinone monoketals have shown poor chemo- and stereoselectivity. To overcome these problems, a highly efficient strategy has been set up based on the temporary conjugate addition of thiophenol to the dipolarophile.