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Comparison of A2E cytotoxicity and phototoxicity with all-trans-retinal in human retinal pigment epithelial cells

DOI: 10.1111/j.1751-1097.2010.00750.x

Source and publish data:

Photochemistry and Photobiology p. 781 - 791 (2010)

Update date:2022-08-11

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Authors:

Wielgus, Albert R.Wielgus, Albert R.

Chignell, Colin F.Chignell, Colin F.

Ceger, PatriciaCeger, Patricia

Roberts, Joan E.Roberts, Joan E.

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Article abstract of DOI:10.1111/j.1751-1097.2010.00750.x

All-trans-retinal is the precursor of A2E, a fluorophore within lipofuscin, which accumulates in human retinal pigment epithelial (hRPE) cells and contributes to age-related macular degeneration. Here we have compared the in vitro dark cytotoxicity and vi

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Full text of DOI:10.1111/j.1751-1097.2010.00750.x

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