A novel ruthenium-catalyzed amination of primary and secondary alcohols

Article abstract of DOI:10.1016/j.tetlet.2006.10.042

An improved method for the N-alkylation of primary amines with primary and secondary alcohols has been developed. Novel, effective catalyst systems, for example, Ru₃(CO)₁₂ combined with tri-o-tolylphosphine or n-butyl-di-1-adamantylphosphine, allow for aminations in a good yield under comparatively mild conditions.