Organic Letters
Experimental procedures and characterization data of
Letter
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X-ray crystallographic data of compounds A and 4a
(
9) For copper-catalyzed reactions of two alkynes and an alkyl or aryl
(
azide in middle selectivity, see: (a) Gerard, B.; Ryan, J.; Beeler, A. B.;
Porco, J. A., Jr Tetrahedron 2006, 62, 6405. (b) Zhang, X.; Hsung, R.
P.; Li, H. Chem. Commun. 2007, 2420.
AUTHOR INFORMATION
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*
(
10) For recent reviews on organic azides as amino source in C−H
functionalization, see: (a) Shin, K.; Kim, H.; Chang, S. Acc. Chem. Res.
2015, 48, 1040. (b) Intrieri, D.; Zardi, P.; Caselli, A.; Gallo, E. Chem.
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ORCID
(
11) For our related works, see: (a) Cheng, D.; Ling, F.; Li, Z.; Yao,
Present Address
W.; Ma, C. Org. Lett. 2012, 14, 3146. (b) Li, Z.; Ling, F.; Cheng, D.;
Ma, C. Org. Lett. 2014, 16, 1822. (c) Ling, F.; Li, Z.; Zheng, C.; Liu,
X.; Ma, C. J. Am. Chem. Soc. 2014, 136, 10914. (d) Yan, X.; Ling, F.;
Zhang, Y.; Ma, C. Org. Lett. 2015, 17, 3536. (e) Cheng, D.; Ling, F.;
Zheng, C.; Ma, C. Org. Lett. 2016, 18, 2435. (f) Wu, J.; Wang, D.;
Wan, Y.; Ma, C. Chem. Commun. 2016, 52, 1661.
‡(
F.L.) Key Laboratory of Pharmaceutical Engineering of
Ministry of Education, College of Pharmaceutical Science,
Zhejiang University of Technology, 18 Chaowang Road,
Hangzhou 310014, China.
(
12) The structure of 3a was unambiguously confirmed upon single-
crystal X-ray diffraction analysis of its analogue A, which was obtained
from 1-ethynyl-4-methoxybenzene and 2a.
Author Contributions
†X.Z. and Y.W. contributed equally.
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
We thank the National Natural Science Foundation of China
21372196 and 21572199) for financial support.
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