A practical solid phase synthesis of quinazoline-2, 4-diones

DOI: 10.1016/S0040-4039(98)01595-0

Source and publish data:

Tetrahedron Letters p. 7235 - 7238 (1998)

Update date:2022-08-12

Topics:

Authors:

Shao, Hui

Colucci, Marcus

Tong, Shaojing

Zhang, Hesheng

Castelhano, Arlindo L.

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Article abstract of DOI:10.1016/S0040-4039(98)01595-0

We describe a practical solid phase synthesis of quinazoline-2,4-diones using a short-chain, high loading capacity, polyethyleneglycol polystyrene copolymer ('PEG₄-PS' resin). The highlights of this synthesis include efficient acyl azide format

Full text of DOI:10.1016/S0040-4039(98)01595-0

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