Tetrahedron Letters p. 4573 - 4576 (1996)
Update date:2022-08-17
Topics:
Dyer, James
Keeling, Steve
Moloney, Mark G.
The α,β-unsaturated lactam 1b has been found to readily undergo conjugate addition reactions with a range of stabilised carbon nucleophiles and Reformatsky reagents under mild conditions in good yield with high diastereoselectivity. This method provides a simple and versatile approach to highly functionalised pyrrolidinones.
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(1990)
