GUAIANE SESQUITERPENES FROM AGARWOOD

Article abstract of DOI:10.1016/0031-9422(91)83206-Z

Key Word Index - Aquilaria agallocha; Thymelaeaceae; agarwood; sesquiterpenes; (-)-guaia-1(10),11-dien-15-ol; (-)-guaia-1(10),11-diene-15-carboxylic acid; methyl guaia-1(10),11-diene-15-carboxylate; (+)-guaia-1(10),11-dien-9-one; (-)-1,10-epoxyguai-11-ene; (-)-guaia-1(10),11-dien-15,2-olide; (-)-rotundone.Seven new sesquiterpenes, all of which have a guaiane skeleton, i.e. (-)-guaia-1(10),11-dien-15-ol, (-)-guaia-1(10),11-diene-15-carboxylic acid, methyl guaia-1(10),11-diene-15-carboxylate, (+)-guaia-1(10),11-dien-9-one, (-)-1,10-epoxyguai-11-ene, (-)-guaia-1(10),11-dien-15,2-olide and (-)-rotundone, have been isolated from Aquilaria agallocha (agarwood).Their structures have been established on the bases of detailed spectroscopic analyses and synthesis.