Facile Synthesis of α-Amino Nitrites Using Lanthanide Triflate as a Lewis Acid Catalyst

Article abstract of DOI:10.1055/s-1997-719

In the presence of a catalytic amount of lanthanide inflate, imines reacted with cyanotrimethylsilane (TMSCN) to afford α-amino nitriles in excellent yields. Although some imines are difficult to prepare and purify, three-component reactions of aldehydes,