Photochemical halogen-exchange reaction of 5-iodouracil-containing oligonucleotides

Article abstract of DOI:10.1016/S0040-4039(99)01082-5

Photoreactions of 5-iododeoxyuridine (d(I)U) and d(I)U-containing oligonucleotides in aqueous solutions in the presence of various inorganic salts have been investigated. In the presence of NaCl and NaBr, d(I)U and d(I)U-containing oligonucleotides undergo an efficient photochemical halogen-exchange reaction to give d(Cl)U and d(Br)U, respectively.