Asymmetric Transformation of DL-4-Thiazolidinecarboxylic Acid

Article abstract of DOI:10.1246/cl.1987.2041

A mixture of DL-4-thiazolidinecarboxylic acid (DL-THC), (+)- or (-)-tartaric acid ((+)- or (-)-TA), and salicylaldehyde in acetic acid was stirred at 80 deg C to give a salt composed of equimolar amounts of L-THC and (-)-TA or that of D-THC and (+)-TA.D- and L-THC with optical purity of 97-99percent were obtained from these salts in 68-78percent yield.