3'-Amidated 3'-deoxyxylofuranose analogues of N6- cyclopentyladenoslnes: A new class of non-xanthine antagonists at the adenosine A1 receptor

Article abstract of DOI:10.1080/07328319808004688

Full adenosine A₁ receptor agonists like CPA and other N⁶-substituted adenosine analogs have previously been shown to become partial agonists upon deletion of the 3'-hydroxyl moiety. The present study further explored the C- 3' site

Full text of DOI:10.1080/07328319808004688

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3′-Amidated 3′-Deoxyxylofuranose
Analogues of N 6--Cyclopentyladenosines:
a New Class of Non-Xanthine Antagonists
at the Adenosine A1 Receptor.
Serge Van Calenbergh a , Adriaan P. IJzerman b & Piet Herdewijn a
a Laboratory for Medicinal Chemistry (FFW) , University of Gent ,
Harelbekestraat 72, B-9000, Gent, Belgium
b Leiden/Amsterdam Center for Drug Research, Division of Medicinal
Chemistry , PO Box 9502, 2300 RA, Leiden, The Netherlands
Published online: 22 Aug 2006.
To cite this article: Serge Van Calenbergh , Adriaan P. IJzerman & Piet Herdewijn (1998) 3′-Amidated
3′-Deoxyxylofuranose Analogues of N 6--Cyclopentyladenosines: a New Class of Non-Xanthine
Antagonists at the Adenosine A1 Receptor., Nucleosides and Nucleotides, 17:9-11, 1571-1576, DOI:
10.1080/07328319808004688
To link to this article: http://dx.doi.org/10.1080/07328319808004688
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