Fixation of Carbon Dioxide with Diphenylcarbodiimide as a Model of Biotin Enzyme Active Site and a Weak Base: The Carboxylation of Fluorene under Mild Conditions

Article abstract of DOI:10.1246/bcsj.64.3738

Carbon dioxide was directly fixed into fluorene in the presence of diphenylcarbodiimide (DPC) as a model of a biotin enzyme active site and potassium hydrogencarbonate.It was considered that not only carbon dioxide but also the hydrogencarbonate ion were the carbon source in the presence of DPC.Weak bases such as potassium acetate, potassium propionate, and potassium formate were also effective for carboxylation.