N-Arylalkyl-N-phenylhydroxylamines as novel photo-induced DNA-cleaving agents

DOI: 10.1039/c39940001427

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1427 - 1428 (1994)

Update date:2022-08-17

Topics:

Authors:

Hwu Hwu

Tsay Tsay

Chen Chen

Patel Patel

Chou Chou

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Article abstract of DOI:10.1039/c39940001427

Single-strand cleavage of DNA was accomplished by photolysis of various N-arylalkyl-N-phenylhydroxylamines under aerobic conditions for 3 h with 312 nm UV light, which functioned as the trigger to initiate the new and controllable DNA cleavage process.

Full text of DOI:10.1039/c39940001427

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