An efficient and convenient synthesis of 4-polyfluoroalkylated pyrrole-3-carboxylates through 1,3-dipolar cycloaddition reaction of polyfluoro-2-alkynoic acid esters with munchnones

DOI: 10.1016/0022-1139(94)03180-8

Source and publish data:

Journal of Fluorine Chemistry p. 5 - 8 (1995)

Update date:2022-08-10

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Authors:

Funabiki, Kazumasa

Ishihara, Takashi

Yamanaka, Hiroki

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Article abstract of DOI:10.1016/0022-1139(94)03180-8

1,3-Dipolar cycloaddition between polyfluoro-2-alkynoic acid esters and 1,3-oxazolium 5-olates (munchnones) readily proceeds in a regiospecific manner under very mild reaction conditions, followed by simultaneous decarboxylation to afford 4-(polyfluoroalk

Full text of DOI:10.1016/0022-1139(94)03180-8

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