An efficient synthesis and resolution of (±)-cis,cis-spiro[4.4]nonane- 1,6-diol

Article abstract of DOI:10.1080/00397919908086023

A four step highly stereoselective synthesis of (±)-cis,cis- spiro[4.4]nonane-1,6-diol (4) in 55% overall yield is described in detail beginning with ethyl 2-oxocyclopentanecarboxylate. A new resolution of diol (±)-4 using (1R)-(+)-camphor is also reported.

Full text of DOI:10.1080/00397919908086023

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Synthetic Communications: An
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An Efficient Synthesis and
Resolution of (±)-cis,cis-
Spiro[4.4]nonane-1,6-diol
a
a
James A. Nieman & Brian A. Keay
a
Department of Chemistry , University of Calgary , Calgary,
Alberta, Canada , T2N 1N4 E-mail:
Published online: 17 Sep 2007.
To cite this article: James A. Nieman & Brian A. Keay (1999) An Efficient Synthesis
and Resolution of (±)-cis,cis-Spiro[4.4]nonane-1,6-diol, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 29:21,
3829-3840, DOI: 10.1080/00397919908086023
To link to this article: http://dx.doi.org/10.1080/00397919908086023
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