Stereoselective synthesis of an optically active axially chiral lactam and its reaction with some electrophiles

DOI: 10.1016/S0040-4039(99)00051-9

Source and publish data:

Tetrahedron Letters p. 1949 - 1952 (1999)

Update date:2022-08-30

Topics:

Authors:

Fujita Fujita

Kitagawa

Izawa Izawa

Dobashi Dobashi

Fukaya Fukaya

Taguchi Taguchi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)00051-9

An optically active form (≥ 98% ee) of N-(ortho-tert-butylphenyl)-5- methoxymethyl-2-pyrrolidinone 3 having axial chirality was prepared from ortho-tert-butylaniline and (S)-5-(methoxymethyl)butylolactone in short steps and a completely stereoselective manner. The reactions of Li-enolate from lactam 3 with various electrophiles proceeded with 3,5-cis-selectivity.

Full text of DOI:10.1016/S0040-4039(99)00051-9

Products guided by the article

Product name:Pentanamide, N-[2-(1,1-dimethylethyl)phenyl]-5-methoxy-4-[(methylsulfonyl)oxy]-, (4S)-

Cas No:223247-63-0

R&D Labs maybe for 223247-63-0

CHINA MEHECO CORPORATION

Contact:+86-10-67147360/67107388

Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China
Changzhou Sunlight Pharmaceutical Co., Ltd.

Contact:+86-519-83131668;83139028;83138042;83137041

Address:JiuliStreet, Benniu Town Changzhou City, Jiangsu Province
Chengdu CSH Pharmaceutical Co.,ltd

Contact:+86-(28)-85321971

Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
Quhua Zhongxing Refrigeration Technology Co.,Ltd.

Contact:+86-5708886618

Address:318 Bulding 2, No.866 Quhua Rd.,Kecheng District
Xinjiang Zhongtai Chemical Co., Ltd.

Contact:+86-991-8788172

Address:NO.78 XISHAN RD.URUMQI，CHINA

Relevant to this article

N-chloro-N-(1,2,2,2-tetrachloro- and 1,2,2-trichloroethyl)-sulfonamides from N,N-dichlorosulfonamides and 1,2-polychloroethenes

Doi:10.1023/B:RUJO.0000010557.39998.2b
(2003)
An efficient and versatile synthesis of apiose and some C-1-aldehyde- and/or 2,3-O-protected derivatives

Doi:10.1016/S0040-4039(02)01084-5
(2002)
Doi:10.1021/jo00821a001
(1971)
Facile preparation of Ni/Al₂O₃ catalytic formulations with the aid of cyclodextrin complexes: Towards highly active and robust catalysts for the direct amination of alcohols

Doi:10.1016/j.jcat.2017.10.006
(2017)
Preparation of 2-amino-2'-hydroxy-1,1'-binaphthyl and N-arylated 2- amino-1,1'-binaphthyl derivatives via palladium-catalyzed amination

Doi:10.1016/S0040-4039(98)02642-2
(1999)
PREPARATION ET REACTIVITE DE QUELQUES ENYNES FLUORES

Doi:10.1016/S0040-4039(00)84738-3
(1986)

Article Doi