Conformationally locked nucleosides. Synthesis and hybridization properties of oligodeoxynucleotides containing 2',4'-C-bridged 2'- deoxynucleosides

DOI: 10.1016/S0960-894X(99)00146-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1147 - 1150 (1999)

Update date:2022-08-25

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Authors:

Wang, Guangyi

Gunic, Esmir

Girardet, Jean-Luc

Stoisavljevic, Vesna

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Article abstract of DOI:10.1016/S0960-894X(99)00146-8

A conformationally locked, 2',4'-C-bridged 2'-daoxyribofuranoside was condense, with silylated pyrimidines to give 2',4'-C-bridged bicyclonucleosides, which were convened to the phosphoramidites and incorporated into oligodeoxynucleotides (ODNs). The hybr

Full text of DOI:10.1016/S0960-894X(99)00146-8

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