COUMARIN GLYCOSIDES OF Haplophyllum perforatum

Article abstract of DOI:10.1007/BF00638768

From the epigeal part of Haplophyllum perforatum we have isolated the coumarins scopoletin (I), scopoletin 7-O-β-D-glucopyranoside (II) and the new coumarin glycoside haploperoside A (III), mp 212-213 deg C, <α>_D²² -37 deg (c 0.24, CH3OH).The acid hydrolysis of (III) formed (I) and the monosaccharides D-glucose and L-rhamnose.Partial hydrolysis of (III) with 10percent acetic acid led to (II) and L-rhamnose.On the basis of the results of a study of UV, IR, and PMR spectra, and also periodate oxidation and polarimetric analysis the structure of 6-methoxy-7-1)-β-D-glucopyranosyloxy>coumarin has been established for (III).Details of the IR, UV, PMR, and mass spectra are given.