A general method for the formation of zinc enolate equivalents from iodoacetates by diisopropylzinc-iodine exchange reaction: Preparation of β-Hydroxy esters

Article abstract of DOI:10.1246/bcsj.73.2825

Diisopropylzinc is found to be a highly efficient reagent for the formation of zinc enolate equivalents from various iodoacetates via iodine-Zinc exchange reaction at room temperature, affording β-Hydroxy esters in high yields by the reaction with aldehydes and ketones.