Behavior of oxotetrahydrobenzo[b]- and [c]thiophenes and their α-hydroxymethylene derivatives in the fischer indole synthesis

Article abstract of DOI:10.3987/com-95-7270

We described an approach to thienocarbazoles via a Fischer indole synthesis starting directly from oxotetrahydrobenzo[b]- and [c]thiophenes or from their α-hydroxymethylene derivatives with a Japp-Klingemann reaction to make the hydrazones which are cyclised under acidic conditions.