Chemistry Letters p. 947 - 948 (1999)
Update date:2022-08-11
Topics:
Akiyama, Takahiko
Takaya, Jun
Kagoshima, Hirotaka
Reported herein are that catalytic amount of conventional Lewis acids activated aldimines in preference to aldehydes, and addition of water to BF3?OEt2 accelerated the Mannich-type reaction significantly to afford β-amino carbonyl compounds in high yields.
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