Steroids 51. An improved synthesis of ORG 2058 and the synthesis of [3H]ORG 2058

DOI: 10.1016/0039-128X(93)90047-Q

Source and publish data:

Steroids p. 115 - 118 (1993)

Update date:2022-08-16

Topics:

Authors:

Bakos, Tamas

Lokoes, Magdalena

Vincze, Iren

Volford, Janos

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Article abstract of DOI:10.1016/0039-128X(93)90047-Q

16α-Ethyl-21-hydroxy-19-norpregn-4-ene-3,20-dione (ORG 2058) is a ligand widely used in progesterone receptor assays. An improved synthesis of the compound is reported, starting from norethisterone acetate. The preparation of the tritiated radioligand [³H]ORG 2058 is also described. (Steroids 58:115-118, 1993).

Full text of DOI:10.1016/0039-128X(93)90047-Q

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