Journal of Organic Chemistry p. 4277 - 4281 (1992)
Update date:2022-08-11
Topics:
Eaton, Philip E.
Xiong, Yusheng
Zhou, Jian Ping
Effective methodology for the synthesis of cubanes with novel substitution patterns is presented.The use of an electron-withdrawing group to accelerate ortho-metalation of amide-activated cubanes is described, as is the effect of the steric bulk of the activating group on the degree of ortho-metalation.
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